Travel RN Jobs Across South Carolina
Comparing travel nurse jobs in South Carolina means reviewing listings across Charleston, Florence, and Orangeburg and other markets — from Charleston's large medical centers and perioperative services to regional hospitals in Columbia and secondary markets throughout the state. Listings include pay, shift structure, and contract length so you can narrow options. Contract demand is steady across both urban systems and smaller community facilities statewide. Use the filters above to narrow... by specialty or city before clicking into any listing to review full details.
South Carolina Travel RN Listings
Compare South Carolina travel RN contracts by specialty, shift, and weekly pay — filter openings below.
- RN
- Allied
- LPN
- Top Specialties
- ER
- ICU
- Inpatient Rehab
- Labor and Delivery
- Med Surg
- MedSurg/Tele
- Operating Room
- PCU
- Stepdown
- Telemetry
- All Specialties
- Admin/Mgmt
- Ambulatory
- Antepartum
- BMT
- Cardiology
- Case Manager
- Cath Lab
- Clinic
- Clinical Decision Unit
- CVICU
- CVOR
- CVPICU
- Detox
- Dialysis
- Director of Nursing
- Electrophysiology
- Endo/GI
- Endoscopy
- Home Health
- Infusion
- Intermediate Care
- Interventional Radiology
- Long Term Care / SNF
- LTAC
- Mother-Baby/Couplet Care/Post Partum
- Neuro
- Neuro/Trauma ICU
- NICU
- Nurse Supervisor
- OB/GYN
- Occupational Health
- Oncology
- Oncology - Pediatric
- Orthopedics
- Outpatient Clinic
- PACU
- PACU/Pre-Post Op
- Pediatric CVOR
- Pediatric ER
- Pediatric OR
- Pediatric PACU
- Pediatrics
- PICU
- Psych
- Pulmonary
- Radiology
- RN First Assistant
- Transplant
- Unit Manager
- Wound Care
- Alabama
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- Connecticut
- DC
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- Georgia
- Hawaii
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- Indiana
- Iowa
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- West Virginia
- Wisconsin
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26 Open Travel Nursing Jobs in South Carolina – May 30th
- Highest Paying
- Days
- Nights
- Flexible/Other
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Labor and Delivery Travel Nurse Job in Florence, SC
McLeod - Regional Medical Center📍Florence, SC$1,996/wk -
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Operating Room Travel Nurse Job in Florence, SC
McLeod - Regional Medical Center📍Florence, SC$1,853/wk -
MedSurg/Tele Travel Nurse Job in Spartanburg, SC
Spartanburg Medical Center📍Spartanburg, SC$1,852/wk -
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ER Travel Nurse Job in Columbia, SC
William Jennings Bryan Dorn Veterans Affairs Medical Center📍Columbia, SC$1,796/wk -
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Labor and Delivery Travel Nurse Job in Columbia, SC
MUSC Health - Columbia Medical Center - Northeast📍Columbia, SC$1,749/wk -
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Inpatient Rehab Travel Nurse Job in Fort Mill, SC
Encompass Health Rehabilitation Hospital of Fort Mill📍Fort Mill, SC$1,349/wk
South Carolina Travel Nursing Market Overview
South Carolina's travel nurse assignments span medical centers in Charleston and Columbia, regional hospitals in Greenville and Spartanburg, and community facilities throughout the state's coastal and inland markets. Contract availability is distributed across both urban health systems and smaller facilities, with steady demand across multiple specialties. As an NLC compact member, South Carolina allows RNs with an active compact license from their home state to practice without obtaining a separate endorsement.

Travel Nursing Jobs - Trending States
Based on current travel job openings, the top 5 highest-paying travel nurse job states are:
- Texas up to $3,518 per week
- California up to $3,418 per week
- New York up to $3,387 per week
- Virginia up to $3,377 per week
- New Jersey up to $3,304 per week
RN Licensing and Assignment Context in South Carolina
The South Carolina Board of Nursing is the authoritative source for current endorsement requirements and processing timelines for travel RNs entering the state. Travelers who need to obtain a South Carolina license before their assignment starts can find current requirements and timeline guidance on our South Carolina RN licensing page. For pay and workforce context, RN employment and wage data published by the Bureau of Labor Statistics is worth reviewing before committing to a South Carolina contract.
South Carolina Travel Nursing Jobs – FAQs
Can I work travel nurse jobs in South Carolina with a compact license?
Yes! South Carolina is part of the Nurse Licensure Compact (NLC). If you already hold an active multistate RN license, you're cleared to work travel nursing jobs in South Carolina without additional licensure. If your state isn’t part of the compact, you’ll need to apply for endorsement through the South Carolina Board of Nursing.
South Carolina Board of Nursing
Contact information
Website: https://llr.sc.gov/
Phone: 803.896.4300
Fees
License by Exam: $90
License by Endorsement: $100
Renewal: $75
Temporary License: $10
Timing
Processing Time: 2 weeks
Valid for: 2 years
Renewal Schedule: April 30th of odd years
General Information
Nursys: Yes
Helpful Links
What kind of housing support does Advantis Medical provide in South Carolina?
How much do travel nurses earn on average in South Carolina?
What benefits do I get as a travel nurse in South Carolina with Advantis Medical?
Travel nurses working in South Carolina with Advantis Medical receive:
- Weekly direct deposit and competitive compensation
- Day One Benefits - Medical, Dental, Vision & 401(k)
- Help with travel & housing accommodations
- Dedicated licensing, onboarding, and credentialing team
- $1,000 Referral Bonus + $250 Bonus for Your Referral for each friend you bring on assignment
What specialties are most in demand for travel nurses in South Carolina?
Hospitals and healthcare systems across the state are actively hiring in:
If you're exploring travel nurse jobs South Carolina, certain specialties stand out due to high demand across South Carolina’s top healthcare facilities. Based on our current openings, here are the specialties with the most active travel nursing jobs in South Carolina.
For Travel RN Jobs, these specialties have the most openings:
- Labor and Delivery with 4 open jobs
- MedSurg/Tele with 4 open jobs
- ER with 3 open jobs
- Oncology with 2 open jobs
- Operating Room with 2 open jobs
For LPN Travel Jobs, these specialties are in highest demand:
- No LPN specialties currently available
For Travel Allied Health Jobs, top openings include:
- Physical Therapy with 33 open jobs
- X-Ray Tech with 3 open jobs
- MRI Tech with 3 open jobs
- CT Tech with 9 open jobs
- Respiratory Therapist with 7 open jobs
Looking for something specific? Click any of the specialties above to explore travel nurse jobs South Carolina by specialty and start your next adventure.