Find Top Travel RN Jobs in South Carolina
Explore travel RN jobs in South Carolina—pay trends, top contracts, and state perks below.
Find 44 travel nurse jobs in South Carolina, updated 14 minutes ago! Just released Operating Room, Med Surg, and ICU travel nursing jobs in South Carolina. Advantis Medical partners with leading hospitals in Charleston, Florence, and Rock Hill. As the #1 travel nurse agency, we deliver high-paying travel nursing jobs in South Carolina, with travel nurses earning up to 17% more than staff jobs. New travel jobs open hourly... with start dates from Dec 23, 2025 to Jan 27, 2026. Start your Palmetto State adventure with Advantis, chosen by thousands of travel nurses nationwide with 700+ 5-star reviews. 1-Click to apply today or sign up for South Carolina job alerts to secure top travel nursing jobs!
44 Open Travel Nursing Jobs in South Carolina – December 13th
- Sort: Highest Pay
- Sort: Newest Jobs
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Nights
13 Weeks
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Travel RN – Operating Room Travel Nurse Job in Florence, SC
McLeod - Regional Medical CenterFlorence, South Carolina
$2,156/wk$2,156 Weekly -
Travel RN – Med Surg Travel Nurse Job in Manning, SC
McLeod Health ClarendonManning, South Carolina
$2,039/wk$2,039 Weekly -
Travel RN – Med Surg Travel Nurse Job in Manning, SC
McLeod Health ClarendonManning, South Carolina
$2,039/wk$2,039 Weekly -
Travel RN – Stepdown Travel Nurse Job in Rock Hill, SC
Piedmont Medical CenterRock Hill, South Carolina
$2,024/wk$2,024 Weekly -
Travel RN – Operating Room Travel Nurse Job in Charleston, SC
Trident Regional Medical CenterCharleston, South Carolina
$1,986/wk$1,986 Weekly -
Travel RN – Operating Room Travel Nurse Job in Charleston, SC
MUSC Health - CharlestonCharleston, South Carolina
$1,984/wk$1,984 Weekly -
Travel RN – Operating Room Travel Nurse Job in Charleston, SC
Roper St Francis HealthcareCharleston, South Carolina
$1,930/wk$1,930 Weekly -
Travel RN – ICU Travel Nurse Job in Florence, SC
MUSC Health Florence Medical CenterFlorence, South Carolina
$1,877/wk$1,877 Weekly
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Travel Nurse Jobs in South Carolina
Advantis Medical specializes in travel nurse jobs in South Carolina, with hundreds placed at respected facilities like MUSC Health - Charleston, MUSC Health Florence Medical Center, and Regency Hospital of Florence. South Carolina has been a priority state for five+ years. Our SC-based Recruiters provide personalized guidance and strong referral rewards. With 44 newly listed travel jobs in South Carolina markets like Charleston, Columbia, and Greenville, travel nursing jobs in South Carolina provide competitive pay ranging from {salary_range_sc} weekly. Join 700+ nurses who’ve certified Advantis #1 for direct access to the most rewarding travel nurse jobs in South Carolina.

Travel Nursing Jobs - Trending States
Based on current travel job openings, the top 5 highest-paying travel nurse job states are:
- California up to $3,458 per week
- New Jersey up to $3,446 per week
- Ohio up to $3,435 per week
- Michigan up to $3,431 per week
- Oregon up to $3,425 per week
Perks of Travel Registered Nurse Jobs in SC
Travel nurse jobs in South Carolina means working in leading healthcare facilities in cities like Charleston, Columbia, and Greenville while enjoying the SC's Southern charm and coastal beauty. From the historic streets of Charleston to the pristine beaches of Hilton Head, travel nursing jobs in South Carolina offer a unique mix of cultural richness and outdoor relaxation. With high-demand specialties, competitive pay, and a lower cost of living, South Carolina is an excellent choice for travel nurses seeking career growth and a laid-back lifestyle. Whether exploring historic plantations or kayaking through the Lowcountry, South Carolina has something for all travel nurses. Start your next adventure with Travel Nurse Jobs in South Carolina today!
South Carolina Travel Nursing Jobs – FAQs
Can I work travel nurse jobs in South Carolina with a compact license?
Yes! South Carolina is part of the Nurse Licensure Compact (NLC). If you already hold an active multistate RN license, you're cleared to work travel nursing jobs in South Carolina without additional licensure. If your state isn’t part of the compact, you’ll need to apply for endorsement through the South Carolina Board of Nursing.
South Carolina Board of Nursing
Contact information
Website: https://llr.sc.gov/
Phone: 803.896.4300
Fees
License by Exam: $90
License by Endorsement: $100
Renewal: $75
Temporary License: $10
Timing
Processing Time: 2 weeks
Valid for: 2 years
Renewal Schedule: April 30th of odd years
General Information
Nurse Licensure Compact: Yes
Nursys: Yes
Helpful Links
What kind of housing support does Advantis Medical provide in South Carolina?
How much do travel nurses earn on average in South Carolina?
What benefits do I get as a travel nurse in South Carolina with Advantis Medical?
Travel nurses working in South Carolina with Advantis Medical receive:
- Weekly direct deposit and competitive compensation
- Day One Benefits - Medical, Dental, Vision & 401(k)
- Help with travel & housing accommodations
- Dedicated licensing, onboarding, and credentialing team
- $500 referral bonuses for each friend you bring on assignment
What specialties are most in demand for travel nurses in South Carolina?
Hospitals and healthcare systems across the state are actively hiring in:
If you're exploring travel nurse jobs South Carolina, certain specialties stand out due to high demand across South Carolina’s top healthcare facilities. Based on our current openings, here are the specialties with the most active travel nursing jobs in South Carolina.
For Travel RN Jobs, these specialties have the most openings:
- Operating Room with 7 open jobs
- Med Surg with 6 open jobs
- ICU with 4 open jobs
- LTAC with 3 open jobs
- Cath Lab with 3 open jobs
For LPN Travel Jobs, these specialties are in highest demand:
- No LPN specialties currently available
For Travel Allied Health Jobs, top openings include:
- Physical Therapy with 11 open jobs
- X-Ray Tech with 2 open jobs
- MRI Tech with 3 open jobs
- CT Tech with 2 open jobs
- Respiratory Therapist with 2 open jobs
Looking for something specific? Click any of the specialties above to explore travel nurse jobs South Carolina by specialty and start your next adventure.
What healthcare systems do travel RNs work with in South Carolina?
Best Paying Jobs in South Carolina
+- Travel RN – ER Travel Nurse Job in Lancaster, SC
- Travel RN – Operating Room Travel Nurse Job in Florence, S...
- Travel RN – Med Surg Travel Nurse Job in Manning, SC
- Travel RN – Stepdown Travel Nurse Job in Rock Hill, SC
- Travel RN – Operating Room Travel Nurse Job in Charleston,...
- Travel RN – Telemetry Travel Nurse Job in Columbia, SC
- Travel RN – Stepdown Travel Nurse Job in Orangeburg, SC
Newest Jobs in South Carolina
+- Travel RN – Stepdown Travel Nurse Job in Orangeburg, SC
- Travel RN – Operating Room Travel Nurse Job in Florence, S...
- Travel RN – Telemetry Travel Nurse Job in Columbia, SC
- Travel RN – Med Surg Travel Nurse Job in Charleston, SC
- Travel RN – Stepdown Travel Nurse Job in Rock Hill, SC
- Travel RN – ER Travel Nurse Job in Lancaster, SC
- Travel RN – Med Surg Travel Nurse Job in Manning, SC